Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 1 Chewable Tablet
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Top Medical Research Studies
8
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
Most Useful Reviews
9
Anxiety improvement
3 people found this helpful
I have been taking it regularly, and my levels have improved remarkably—from 22 to 70! My cold sores have reduced significantly, and I’ve not caught a cold since. My insomnia has slightly improved too.
Read More
9
Cold allergy help
1 people found this helpful
I've been using vitamin D3 for a month now, and it has significantly reduced my cold allergies! I highly recommend it for anyone suffering from cold sores.
Read More
8
Asthma relief
3 people found this helpful
Although I usually rely on homeopathy, this has been beneficial for my asthma. Taking it when I have cold sores, such as a sore throat, helps me recover quickly. It also has a delightful berry flavour.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Anxiety improvement
3 people found this helpful
I have been taking it regularly, and my levels have improved remarkably—from 22 to 70! My cold sores have reduced significantly, and I’ve not caught a cold since. My insomnia has slightly improved too.
Read More
9
Cold allergy help
1 people found this helpful
I've been using vitamin D3 for a month now, and it has significantly reduced my cold allergies! I highly recommend it for anyone suffering from cold sores.
Read More
8
Asthma relief
3 people found this helpful
Although I usually rely on homeopathy, this has been beneficial for my asthma. Taking it when I have cold sores, such as a sore throat, helps me recover quickly. It also has a delightful berry flavour.
Read More
7.5
Quick recovery
1 people found this helpful
My children adore these vitamins due to their great taste and effectiveness. During colds, I double the dosage, and it has helped them to recover from cold sores faster.
Read More
7.5
Cold coping
1 people found this helpful
I ordered these vitamins for my child, and I’ve found them highly effective. They help with coping with cold sores, and I pair them with zinc and vitamin C for better health.
Read More
Frequently Asked Questions
9
Cold allergy help
1 people found this helpful
I've been using vitamin D3 for a month now, and it has significantly reduced my cold allergies! I highly recommend it for anyone suffering from cold sores.
7.5
Quick recovery
1 people found this helpful
My children adore these vitamins due to their great taste and effectiveness. During colds, I double the dosage, and it has helped them to recover from cold sores faster.
9
Anxiety improvement
3 people found this helpful
I have been taking it regularly, and my levels have improved remarkably—from 22 to 70! My cold sores have reduced significantly, and I’ve not caught a cold since. My insomnia has slightly improved too.
8
Asthma relief
3 people found this helpful
Although I usually rely on homeopathy, this has been beneficial for my asthma. Taking it when I have cold sores, such as a sore throat, helps me recover quickly. It also has a delightful berry flavour.
7.5
Cold coping
1 people found this helpful
I ordered these vitamins for my child, and I’ve found them highly effective. They help with coping with cold sores, and I pair them with zinc and vitamin C for better health.
References
- Santamaria P, Bowyer RCE, Nibali L. Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort. Arch Oral Biol. 2023;145:105587. doi:10.1016/j.archoralbio.2022.105587
